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NDB ID: NA1064    PDB ID: 3REJ 


Title:

2.55 ANGSTROM CRYSTAL STRUCTURE OF THE NUCLEOSOME CORE PARTICLE ASSEMBLED WITH A 146 BP ALPHA-SATELLITE DNA (NCP146B)

Molecular Description:

Histone H3.2
Histone H4
Histone H2A type 1
Histone H2B 1.1/DNA complex

Deposited:

2011-04-04

Released:

2012-03-14

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Wu, B., Davey, G.E., Nazarov, A.A., Dyson, P.J., Davey, C.A.
Specific DNA structural attributes modulate platinum anticancer drug site selection and cross-link generation. 
Nucleic Acids Res., 39, pp. 8200 - 8212, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 106.067   b = 109.374   c = 176.465 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2343 for 60540 reflections in the resolution range 92.85 to 2.55 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)