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NDB ID: NA1067    PDB ID: 3RH4 


Title:

DNA POLYMERASE BETA WITH A DIDEOXY-TERMINATED PRIMER WITH AN INCOMING RIBONUCLEOTIDE (RCTP)

Molecular Description:

DNA polymerase beta (E.C.2.7.7.7
4.2.99.-)/DNA complex

Deposited:

2011-04-11

Released:

2011-07-06

Structural Keywords:

B DOUBLE HELIX, NICKED

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Cavanaugh, N.A., Beard, W.A., Batra, V.K., Perera, L., Pedersen, L.G., Wilson, S.H.
Molecular insights into DNA polymerase deterrents for ribonucleotide insertion. 
J.Biol.Chem., 286, pp. 31650 - 31660, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 51.17   b = 79.79   c = 55.0 (Ångstroms)

α = 90.0   β = 107.95   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1818 for 27776 reflections in the resolution range 22.594 to 1.918 Ångstroms with Fobs >  0.04 sigma(Fobs) and with I >  0.0 sigma(I)