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NDB ID: NA1159    PDB ID: 3S8U 


Title:

CRYSTAL STRUCTURE OF A 2-AZIDO-ADENINE-MODIFIED RNA

Molecular Description:

Ecoli 23 S rRNA Sarcin Ricin loop

Structural Keywords:

SINGLE STRAND, LOOP, HAIRPIN LOOP, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Fauster, K., Hartl, M., Santner, T., Aigner, M., Kreutz, C., Bister, K., Ennifar, E., Micura, R.
2'-Azido RNA, a Versatile Tool for Chemical Biology: Synthesis, X-ray Structure, siRNA Applications, Click Labeling. 
Acs Chem.Biol., 7, pp. 581 - 589, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43

Cell Constants:

a = 29.57   b = 29.57   c = 76.34 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.7_650) program. The R value is 0.1445 for 19980 reflections in the resolution range 27.574 to 1.2 Ångstroms with Fobs >  2.01 sigma(Fobs) and with I >  0.0 sigma(I)