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NDB ID: NA1171    PDB ID: 3SJ2 


Title:

A CRYSTAL STRUCTURE OF A MODEL OF THE REPEATING R(CGG) TRANSCRIPT FOUND IN FRAGILE X SYNDROME

Molecular Description:

5'-R(*UP*UP*GP*GP*GP*CP*CP*GP*GP*CP*GP*GP*CP*GP*GP*GP*UP*CP*C)-3'

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Kumar, A., Fang, P., Park, H., Guo, M., Nettles, K.W., Disney, M.D.
A Crystal Structure of a Model of the Repeating r(CGG) Transcript Found in Fragile X Syndrome. 
Chembiochem, 12, pp. 2140 - 2142, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 55.66   b = 32.32   c = 69.442 (Ångstroms)

α = 90.0   β = 108.95   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.7_650) program. The R value is 0.1571 for 22170 reflections in the resolution range 27.543 to 1.36 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)