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NDB ID: NA1186    PDB ID: 3SNP 


Title:

CRYSTAL STRUCTURE ANALYSIS OF IRON REGULATORY PROTEIN 1 IN COMPLEX WITH FERRITIN H IRE RNA

Molecular Description:

Cytoplasmic aconitate hydratase (E.C.4.2.1.3)/RNA complex

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP, BULGES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Walden, W.E., Selezneva, A.I., Dupuy, J., Volbeda, A., Fontecilla-Camps, J.C., Theil, E.C., Volz, K.
Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. 
Science, 314, pp. 1903 - 1908, 2006.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 109.555   b = 80.851   c = 142.873 (Ångstroms)

α = 90.0   β = 92.03   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.2 program. The R value is 0.199 for 57957 reflections in the resolution range 99.0 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)