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NDB ID: NA1241    PDB ID: 3T1Y 


Title:

STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT COMPLEXED WITH A HUMAN ANTI-CODON STEM LOOP (HASL) OF TRANSFER RNA LYSINE 3 (TRNALYS3) BOUND TO AN MRNA WITH AN AAG-CODON IN THE A-SITE AND PAROMOMYCIN

Molecular Description:

PROTEIN/RNA Complex

Structural Keywords:

A SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 3 nucleic acid sequences

Protein Sequence:

Click to show/hide 20 protein sequences

Primary Citation:

Vendeix, F.A., Murphy, F.V., Cantara, W.A., Leszczynska, G., Gustilo, E.M., Sproat, B., Malkiewicz, A., Agris, P.F.
Human tRNA(Lys3)(UUU) Is Pre-Structured by Natural Modifications for Cognate and Wobble Codon Binding through Keto-Enol Tautomerism. 
J.Mol.Biol., 416, pp. 467 - 485, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 400.972   b = 400.972   c = 174.647 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.3 program. The R value is 0.0 for 341667 reflections in the resolution range 29.89 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)