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NDB ID: NA1289    PDB ID: 3THW 


Title:

HUMAN MUTSBETA COMPLEXED WITH AN IDL OF 4 BASES (LOOP4) AND ADP

Molecular Description:

DNA mismatch repair protein Msh2
DNA mismatch repair protein Msh3/DNA complex

Deposited:

2011-08-19

Released:

2011-12-21

Structural Keywords:

B DOUBLE HELIX, HAIRPIN LOOP, BULGES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Gupta, S., Gellert, M., Yang, W.
Mechanism of mismatch recognition revealed by human MutSbeta bound to unpaired DNA loops 
Nat.Struct.Mol.Biol., 19, pp. 72 - 78, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 105.84   b = 116.13   c = 180.04 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2291 for 38509 reflections in the resolution range 32.53 to 3.09 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)