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NDB ID: NA1313    PDB ID: 3TUP 


Title:

CRYSTAL STRUCTURE OF HUMAN MITOCHONDRIAL PHERS COMPLEXED WITH TRNAPHE IN THE ACTIVE OPEN STATE

Molecular Description:

Phenylalanyl-tRNA synthetase
mitochondrial (E.C.6.1.1.20)/RNA complex

Structural Keywords:

T SINGLE STRAND, LOOP, HAIRPIN LOOP, FLIPPED-OUT BASES, BASE TRIPLET

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Klipcan, L., Moor, N., Finarov, I., Kessler, N., Sukhanova, M., Safro, M.G.
Crystal Structure of Human Mitochondrial PheRS Complexed with tRNA(Phe) in the Active ""Open"" State. 
J.Mol.Biol., 415, pp. 527 - 537, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 116.041   b = 116.041   c = 123.276 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.245 for 18615 reflections in the resolution range 38.94 to 3.05 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)