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NDB ID: NA1321    PDB ID: 3SYW 


Title:

CRYSTAL STRUCTURE OF THE TRIPLET REPEAT IN MYOTONIC DYSTROPHY REVEALS HETEROGENEOUS 1X1 NUCLEOTIDE UU INTERNAL LOOP CONFORMATIONS

Molecular Description:

5'-R(*UP*UP*GP*GP*GP*CP*CP*UP*GP*CP*UP*GP*CP*UP*GP*GP*UP*CP*C)-3'

Structural Keywords:

DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Kumar, A., Park, H., Fang, P., Parkesh, R., Guo, M., Nettles, K.W., Disney, M.D.
Crystal Structure of the Triplet Repeat in Myotonic Dystrophy Reveals Heterogeneous 1x1 Nucleotide UU Internal Loop Conformations 
Biochemistry, 50, pp. 9928 - 9935, 2011.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3

Cell Constants:

a = 46.535   b = 46.535   c = 135.001 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.168 for 16068 reflections in the resolution range 34.6 to 1.57 Ångstroms with Fobs >  0.15 sigma(Fobs) and with I >  0.0 sigma(I)