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NDB ID: NA1478    PDB ID: 3V4I 


Title:

CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) WITH DNA AND AZTTP

Molecular Description:

Gag-Pol polyprotein/DNA complex

Deposited:

2011-12-15

Released:

2012-01-18

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Das, K., Martinez, S.E., Bauman, J.D., Arnold, E.
HIV-1 reverse transcriptase complex with DNA and nevirapine reveals non-nucleoside inhibition mechanism. 
Nat.Struct.Mol.Biol., 19, pp. 253 - 259, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 90.053   b = 132.647   c = 138.014 (Ångstroms)

α = 90.0   β = 98.12   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2296 for 73170 reflections in the resolution range 45.543 to 2.7983 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)