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NDB ID: NA1487    PDB ID: 3V11 


Title:

STRUCTURE OF THE TERNARY INITIATION COMPLEX AIF2:GDPNP:METHIONYLATED INITIATOR TRNA

Molecular Description:

Translation initiation factor 2 subunit gamma
Translation initiation factor 2 subunit alpha
Translation initiation factor 2 subunit beta/METHIONYL-TRNA

Structural Keywords:

T SINGLE STRAND, LOOPS, HAIRPIN LOOP, HAMMERHEAD

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Schmitt, E., Panvert, M., Lazennec-Schurdevin, C., Coureux, P.D., Perez, J., Thompson, A., Mechulam, Y.
Structure of the ternary initiation complex aIF2-GDPNP-methionylated initiator tRNA. 
Nat.Struct.Mol.Biol., 19, pp. 450 - 454, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 2 1

Cell Constants:

a = 133.0   b = 133.0   c = 167.2 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.7.2_869) program. The R value is 0.2654 for 7627 reflections in the resolution range 47.426 to 5.0 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)