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NDB ID: NA1513    PDB ID: 3VD0 


Title:

STRUCTURE OF P73 DNA BINDING DOMAIN TETRAMER MODULATES P73 TRANSACTIVATION

Molecular Description:

TAp73 TUMOUR SUPPRESSOR PROTEIN DNA BINDING DOMAIN/DNA

Deposited:

2012-01-04

Released:

2012-04-18

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ethayathulla, A.S., Tse, P.W., Monti, P., Nguyen, S., Inga, A., Fronza, G., Viadiu, H.
Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. 
Proc.Natl.Acad.Sci.USA, 109, pp. 6066 - 6071, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 82.09   b = 104.521   c = 122.994 (Ångstroms)

α = 90.0   β = 96.18   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS program. The R value is 0.235 for 43405 reflections in the resolution range 19.92 to 2.95 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)