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NDB ID: NA1587    PDB ID: 4DK9 


Title:

CRYSTAL STRUCTURE OF MBD4 CATALYTIC DOMAIN BOUND TO ABASIC DNA

Molecular Description:

Methyl-CpG-binding domain protein 4/DNA Complex

Deposited:

2012-02-03

Released:

2012-04-25

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Manvilla, B.A., Maiti, A., Begley, M.C., Toth, E.A., Drohat, A.C.
Crystal Structure of Human Methyl-Binding Domain IV Glycosylase Bound to Abasic DNA. 
J.Mol.Biol., 420, pp. 164 - 175, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 40.999   b = 55.161   c = 122.193 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.0 for 7583 reflections in the resolution range 61.1 to 2.76 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)