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NDB ID: NA1642    PDB ID: 4DWA 


Title:

CRYSTAL STRUCTURE OF AN ACTIVE-SITE MUTANT OF THE GLYCOPROTEIN ERNS FROM THE PESTIVIRUS BVDV-1 IN COMPLEX WITH A CPUPC TRINUCLEOTIDE

Molecular Description:

E(rns) glycoprotein

Deposited:

2012-02-24

Released:

2012-05-23

Structural Keywords:

SINGLE STRAND

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Krey, T., Bontems, F., Vonrhein, C., Vaney, M.C., Bricogne, G., Rumenapf, T., Rey, F.A.
Crystal Structure of the Pestivirus Envelope Glycoprotein E(rns) and Mechanistic Analysis of Its Ribonuclease Activity. 
Structure, 20, pp. 862 - 873, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 105.213   b = 105.213   c = 210.904 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the BUSTER-TNT program. The R value is 0.197 for 13291 reflections in the resolution range 41.82 to 3.01 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)