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NDB ID: NA1702    PDB ID: 4ECS     NAKB: NA1702 


Title:

HUMAN DNA POLYMERASE ETA - DNA TERNARY COMPLEX: REACTION IN THE AT CRYSTAL AT PH 7.0 FOR 80 SEC

Molecular Description:

DNA polymerase eta (E.C.2.7.7.7)/DNA

Deposited:

2012-03-26

Released:

2012-07-11

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Nakamura, T., Zhao, Y., Yamagata, Y., Hua, Y.J., Yang, W.
Watching DNA polymerase eta make a phosphodiester bond 
Nature, 487, pp. 196 - 201, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.786   b = 98.786   c = 82.431 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1818 for 30830 reflections in the resolution range 30.102 to 1.951 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)