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NDB ID: NA1773    PDB ID: 4F3T     NAKB(beta): NA1773 


Title:

HUMAN ARGONAUTE-2 - MIR-20A COMPLEX

Molecular Description:

Protein argonaute-2 (E.C.3.1.26.-)/RNA

Deposited:

2012-05-09

Released:

2012-05-30

Structural Keywords:

SINGLE STRAND, FLIPPED-OUT BASES

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Elkayam, E., Kuhn, C.D., Tocilj, A., Haase, A.D., Greene, E.M., Hannon, G.J., Joshua-Tor, L.
The Structure of Human Argonaute-2 in Complex with miR-20a. 
Cell(Cambridge,Mass.), 150, pp. 100 - 110, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 63.427   b = 107.651   c = 68.718 (Ångstroms)

α = 90.0   β = 106.69   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.208 for 41069 reflections in the resolution range 47.438 to 2.25 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)