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NDB ID: NA1817    PDB ID: 4F8U 


Title:

CRYSTAL STRUCTURE OF THE BACTERIAL RIBOSOMAL DECODING SITE IN COMPLEX WITH SISOMICIN (C2 FORM)

Molecular Description:

5'-R(P*UP*GP*CP*GP*UP*CP*AP*CP*AP*CP*CP*GP*GP*UP*GP*AP*AP*GP*UP*CP*GP*C)-3'
Sisomicin

Structural Keywords:

A DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Kondo, J., Koganei, M., Kasahara, T.
Crystal Structure and Specific Binding Mode of Sisomicin to the Bacterial Ribosomal Decoding Site
ACS MED.CHEM.LETT., , pp. - , 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 115.11   b = 28.75   c = 43.74 (Ångstroms)

α = 90.0   β = 97.17   γ = 90.0 (degrees)

Refinement:

The structure was refined using the CNS 1.3 program. The R value is 0.0 for 9679 reflections in the resolution range 18.3 to 2.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)