A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 9-Feb-2023 number of released structures: 12635
Search for released structures

NDB ID: NA1826    PDB ID: 4AV1     NAKB(beta): NA1826 


Title:

CRYSTAL STRUCTURE OF THE HUMAN PARP-1 DNA BINDING DOMAIN IN COMPLEX WITH DNA

Molecular Description:

POLY [ADP-RIBOSE] POLYMERASE 1 (E.C.2.4.2.30)

Deposited:

2012-05-23

Released:

2012-06-13

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ali, A.A.E., Timinszky, G., Arribas-Bosacoma, R., Kozlowski, M., Hassa, P.O., Hassler, M., Ladurner, A.G., Pearl, L.H., Oliver, A.W.
The Zinc-Finger Domains of Parp1 Cooperate to Recognise DNA Strand-Breaks 
Nat.Struct.Mol.Biol., 19, pp. 685 - , 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 163.978   b = 59.504   c = 61.582 (Ångstroms)

α = 90.0   β = 101.18   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2305 for 9863 reflections in the resolution range 44.353 to 3.1 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)