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NDB ID: NA1920    PDB ID: 4FXD 


Title:

CRYSTAL STRUCTURE OF YEAST DNA POLYMERASE ALPHA BOUND TO DNA/RNA

Molecular Description:

DNA polymerase alpha catalytic subunit A (E.C.2.7.7.7)/DNA/RNA complex

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Perera, R.L., Torella, R., Klinge, S., Kilkenny, M.L., Maman, J.D., Pellegrini, L.
Mechanism for priming DNA synthesis by yeast DNA Polymerase alpha 
eLife, 2, pp. e00482 - , 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1

Cell Constants:

a = 72.14   b = 74.77   c = 116.99 (Ångstroms)

α = 82.26   β = 72.57   γ = 82.4 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: dev_1078) program. The R value is 0.2555 for 45009 reflections in the resolution range 55.526 to 3.0 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)