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NDB ID: NA1962    PDB ID: 4GHA 


Title:

CRYSTAL STRUCTURE OF MARBURG VIRUS VP35 RNA BINDING DOMAIN BOUND TO 12-BP DSRNA

Molecular Description:

Polymerase cofactor VP35/RNA complex

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Bale, S., Julien, J.P., Bornholdt, Z.A., Kimberlin, C.R., Halfmann, P., Zandonatti, M.A., Kunert, J., Kroon, G.J., Kawaoka, Y., Macrae, I.J., Wilson, I.A., Saphire, E.O.
Marburg Virus VP35 Can Both Fully Coat the Backbone and Cap the Ends of dsRNA for Interferon Antagonism. 
Plos Pathog., 8, pp. e1002916 - e1002916, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 36.593   b = 99.191   c = 81.801 (Ångstroms)

α = 90.0   β = 89.92   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.5.0102 program. The R value is 0.21073 for 18981 reflections in the resolution range 81.8 to 2.5 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  1.0 sigma(I)