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NDB ID: NA1972    PDB ID: 4GHL 


Title:

STRUCTURAL BASIS FOR MARBURG VIRUS VP35 MEDIATE IMMUNE EVASION MECHANISMS

Molecular Description:

PROTEIN/RNA Complex

Structural Keywords:

DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ramanan, P., Edwards, M.R., Shabman, R.S., Leung, D.W., Endlich-Frazier, A.C., Borek, D.M., Otwinowski, Z., Liu, G., Huh, J., Basler, C.F., Amarasinghe, G.K.
Structural basis for Marburg virus VP35-mediated immune evasion mechanisms. 
Proc.Natl.Acad.Sci.USA, 109, pp. 20661 - 20666, 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 83.771   b = 93.384   c = 102.071 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.6.0117 program. The R value is 0.18999 for 48487 reflections in the resolution range 37.87 to 2.02 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)