A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 5-Aug-2020 number of released structures: 10886
Search for released structures

NDB ID: NA2038    PDB ID: 4H10 


Title:

INTERMOLECULAR RECOGNITION REVEALED BY THE COMPLEX STRUCTURE OF HUMAN CLOCK-BMAL1 BASIC HELIX-LOOP-HELIX DOMAINS WITH E-BOX DNA

Molecular Description:

Aryl hydrocarbon receptor nuclear translocator-like protein 1
Circadian locomoter output cycles protein kaput (E.C.2.3.1.48)/DNA complex

Deposited:

2012-09-10

Released:

2012-12-26

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Wang, Z., Wu, Y., Li, L., Su, X.D.
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA. 
Cell Res., 23, pp. 213 - 224, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 31 2 1

Cell Constants:

a = 98.74   b = 98.74   c = 62.88 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1975 for 14045 reflections in the resolution range 38.8 to 2.402 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)