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NDB ID: NA2042    PDB ID: 4AY2 


Title:

CAPTURING 5' TRI-PHOSPHORYLATED RNA DUPLEX BY RIG-I

Molecular Description:

PROBABLE ATP-DEPENDENT RNA HELICASE DDX58 (E.C.3.6.4.13)

Structural Keywords:

SINGLE STRAND, HAIRPIN LOOP

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Luo, D., Kohlway, A., Vela, A., Pyle, A.M.
Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I. 
Structure, 20, pp. 1983 - , 2012.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 47.745   b = 76.156   c = 221.222 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC 5.7.0029 program. The R value is 0.22153 for 19224 reflections in the resolution range 24.9 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)