A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 13-Nov-2019 number of released structures: 10455
Search for released structures

NDB ID: NA2053    PDB ID: 4HF2 


Title:

CRYSTAL STRUCTURE OF E43A ISCR MUTANT BOUND TO ITS PROMOTER

Molecular Description:

HTH-type transcriptional regulator IscR/DNA

Deposited:

2012-10-04

Released:

2013-05-08

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Rajagopalan, S., Teter, S.J., Zwart, P.H., Brennan, R.G., Phillips, K.J., Kiley, P.J.
Studies of IscR reveal a unique mechanism for metal-dependent regulation of DNA binding specificity. 
Nat.Struct.Mol.Biol., 20, pp. 740 - 747, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 48.622   b = 75.184   c = 186.448 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.233 for 12019 reflections in the resolution range 43.11 to 2.99 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)