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NDB ID: NA2081    PDB ID: 4HJE 


Title:

CRYSTAL STRUCTURE OF P53 CORE DOMAIN IN COMPLEX WITH DNA

Molecular Description:

Cellular tumor antigen p53

Deposited:

2012-10-12

Released:

2013-07-17

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chen, Y., Zhang, X., Dantas Machado, A.C., Ding, Y., Chen, Z., Qin, P.Z., Rohs, R., Chen, L.
Structure of p53 binding to the BAX response element reveals DNA unwinding and compression to accommodate base-pair insertion. 
Nucleic Acids Res., 41, pp. 8368 - 8376, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 65.42   b = 93.88   c = 145.634 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1891 for 67896 reflections in the resolution range 48.665 to 1.907 Ångstroms with Fobs >  0.11 sigma(Fobs) and with I >  0.0 sigma(I)