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NDB ID: NA2087    PDB ID: 4HKQ 


Title:

XMRV REVERSE TRANSCRIPTASE IN COMPLEX WITH RNA/DNA HYBRID

Molecular Description:

Reverse transcriptase/ribonuclease H p80 (E.C.2.7.7.49
2.7.7.7
3.1.26.4)/RNA/DNA

Structural Keywords:

A DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Nowak, E., Potrzebowski, W., Konarev, P.V., Rausch, J.W., Bona, M.K., Svergun, D.I., Bujnicki, J.M., Le Grice, S.F., Nowotny, M.
Structural analysis of monomeric retroviral reverse transcriptase in complex with an RNA/DNA hybrid 
Nucleic Acids Res., 41, pp. 3874 - 3887, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 43 21 2

Cell Constants:

a = 98.132   b = 98.132   c = 201.824 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.7_650) program. The R value is 0.227 for 19172 reflections in the resolution range 29.661 to 3.04 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)