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NDB ID: NA2172    PDB ID: 4IG8 


Title:

STRUCTURAL BASIS FOR CYTOSOLIC DOUBLE-STRANDED RNA SURVEILLANCE BY HUMAN OAS1

Molecular Description:

2'-5'-oligoadenylate synthase 1 (E.C.2.7.7.-)

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Donovan, J., Dufner, M., Korennykh, A.
Structural basis for cytosolic double-stranded RNA surveillance by human oligoadenylate synthetase 1. 
Proc.Natl.Acad.Sci.USA, 110, pp. 1652 - 1657, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 71.2   b = 93.2   c = 98.6 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.8_1069) program. The R value is 0.2311 for 18574 reflections in the resolution range 67.7 to 2.7 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)