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NDB ID: NA2183    PDB ID: 4I3H 


Title:

A THREE-GATE STRUCTURE OF TOPOISOMERASE IV FROM STREPTOCOCCUS PNEUMONIAE

Molecular Description:

Topoisomerase IV subunit B
DNA topoisomerase 4 subunit A chimera (E.C.5.99.1.3)/DNA Complex

Deposited:

2012-11-26

Released:

2013-08-28

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Laponogov, I., Veselkov, D.A., Crevel, I.M., Pan, X.S., Fisher, L.M., Sanderson, M.R.
Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. 
Nucleic Acids Res., 41, pp. 9911 - 9923, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 42 21 2

Cell Constants:

a = 160.6   b = 160.6   c = 280.56 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1886 for 39825 reflections in the resolution range 71.823 to 3.7 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)