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NDB ID: NA2249    PDB ID: 4J19     NAKB(beta): NA2249 


Title:

STRUCTURE OF A NOVEL TELOMERE REPEAT BINDING PROTEIN BOUND TO DNA

Molecular Description:

Homeobox-containing protein 1/DNA Complex

Deposited:

2013-02-01

Released:

2013-05-29

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Kappei, D., Butter, F., Benda, C., Scheibe, M., Draskovic, I., Stevense, M., Novo, C.L., Basquin, C., Araki, M., Araki, K., Krastev, D.B., Kittler, R., Jessberger, R., Londono-Vallejo, J.A., Mann, M., Buchholz, F.
HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment. 
Embo J., 32, pp. 1681 - 1701, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 111.433   b = 116.49   c = 75.67 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1741 for 11682 reflections in the resolution range 46.155 to 2.9 Ångstroms with Fobs >  2.01 sigma(Fobs) and with I >  0.0 sigma(I)