NDB ID: NA2255    PDB ID: 4J9O     NAKB(beta): NA2255 

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Title:

HUMAN DNA POLYMERASE ETA-DNA TERNARY COMPLEX: PRIMER EXTENSION AFTER A T:G MISPAIR

Molecular Description:

DNA polymerase eta (E.C.2.7.7.7)/DNA complex

Deposited:

2013-02-16

Released:

2013-05-01

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Zhao, Y., Gregory, M.T., Biertumpfel, C., Hua, Y.J., Hanaoka, F., Yang, W.
Mechanism of somatic hypermutation at the WA motif by human DNA polymerase eta. 
Proc.Natl.Acad.Sci.USA, 110, pp. 8146 - 8151, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 99.49   b = 99.49   c = 81.58 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2098 for 13641 reflections in the resolution range 27.091 to 2.597 Ångstroms with Fobs >  1.37 sigma(Fobs) and with I >  0.0 sigma(I)

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Biological Assembly coordinates (pdb format) 1

Structure Factors (cif format)

Coordinates (pdb format, Unix compressed(.gz))

Coordinates (cif format, Unix compressed(.gz))

NMR Restraints (cif format, Unix compressed(.gz))

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