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NDB ID: NA2272    PDB ID: 3W6V 


Title:

CRYSTAL STRUCTURE OF THE DNA-BINDING DOMAIN OF ADPA, THE GLOBAL TRANSCRIPTIONAL FACTOR, IN COMPLEX WITH A TARGET DNA

Molecular Description:

AdpA/DNA

Deposited:

2013-02-22

Released:

2013-09-18

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Yao, M.D., Ohtsuka, J., Nagata, K., Miyazono, K., Zhi, Y., Ohnishi, Y., Tanokura, M.
Complex Structure of the DNA-binding Domain of AdpA, the Global Transcription Factor in Streptomyces griseus, and a Target Duplex DNA Reveals the Structural Basis of Its Tolerant DNA Sequence Specificity 
J.Biol.Chem., 288, pp. 31019 - 31029, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 2 2 21

Cell Constants:

a = 76.51   b = 100.64   c = 100.91 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.23787 for 8039 reflections in the resolution range 19.5 to 2.95 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)