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NDB ID: NA2327    PDB ID: 4JUO 


Title:

A LOW-RESOLUTION THREE-GATE STRUCTURE OF TOPOISOMERASE IV FROM STREPTOCOCCUS PNEUMONIAE IN SPACE GROUP H32

Molecular Description:

DNA topoisomerase 4 subunit A (E.C.5.99.1.3)
DNA topoisomerase 4 subunit B (E.C.5.99.1.3)/DNA

Deposited:

2013-03-25

Released:

2013-08-28

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 4 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Laponogov, I., Veselkov, D.A., Crevel, I.M., Pan, X.S., Fisher, L.M., Sanderson, M.R.
Structure of an 'open' clamp type II topoisomerase-DNA complex provides a mechanism for DNA capture and transport. 
Nucleic Acids Res., 41, pp. 9911 - 9923, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

H 3 2

Cell Constants:

a = 213.58   b = 213.58   c = 211.83 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2498 for 3701 reflections in the resolution range 46.442 to 6.53 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)