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NDB ID: NA2461    PDB ID: 4KRF 


Title:

STRUCTURE OF HUMAN ARGONAUTE-1 LET-7 COMPLEX

Molecular Description:

Protein argonaute-1

Deposited:

2013-05-16

Released:

2013-06-19

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Faehnle, C.R., Elkayam, E., Haase, A.D., Hannon, G.J., Joshua-Tor, L.
The making of a slicer: activation of human argonaute-1. 
Cell Rep, 3, pp. 1901 - 1909, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 70.39   b = 97.73   c = 72.7 (Ångstroms)

α = 90.0   β = 110.89   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1772 for 50614 reflections in the resolution range 40.568 to 2.101 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)