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NDB ID: NA2470    PDB ID: 4KZD     NAKB(beta): NA2470 


Title:

CRYSTAL STRUCTURE OF AN RNA APTAMER IN COMPLEX WITH FLUOROPHORE AND FAB

Molecular Description:

BL3-6 Fab antibody
rna

Deposited:

2013-05-29

Released:

2014-06-18

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Huang, H., Suslov, N.B., Li, N.S., Shelke, S.A., Evans, M.E., Koldobskaya, Y., Rice, P.A., Piccirilli, J.A.
A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. 
Nat.Chem.Biol., 10, pp. 686 - 691, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 148.425   b = 79.602   c = 95.21 (Ångstroms)

α = 90.0   β = 111.65   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1803 for 52457 reflections in the resolution range 46.687 to 2.186 Ångstroms with Fobs >  1.34 sigma(Fobs) and with I >  0.0 sigma(I)