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NDB ID: NA2570    PDB ID: 2YPA     NAKB(beta): NA2570 


Title:

STRUCTURE OF THE SCL:E47:LMO2:LDB1 COMPLEX BOUND TO DNA

Molecular Description:

T-CELL ACUTE LYMPHOCYTIC LEUKEMIA PROTEIN 1
TRANSCRIPTION FACTOR E2-ALPHA
RHOMBOTIN-2
LIM DOMAIN-BINDING PROTEIN 1

Deposited:

2012-10-30

Released:

2013-07-31

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

El Omari, K., Hoosdally, S.J., Tuladhar, K., Karia, D., Hall-Ponsele, E., Platonova, O., Vyas, P., Patient, R., Porcher, C., Mancini, E.J.
Structural Basis for Lmo2-Driven Recruitment of the Scl:E47bHLH Heterodimer to Hematopoietic-Specific Transcriptional Targets. 
Cell Rep., 4, pp. 135 - , 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

F 2 2 2

Cell Constants:

a = 102.966   b = 141.044   c = 148.793 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.22614 for 12714 reflections in the resolution range 30.15 to 2.8 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)