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NDB ID: NA2723    PDB ID: 4MKY 


Title:

POLYMERASE DOMAIN FROM MYCOBACTERIUM TUBERCULOSIS LIGASE D IN COMPLEX WITH AN ANNEALED DOUBLE-STRAND DNA BREAK.

Molecular Description:

DNA ligase-like protein Rv0938/MT0965

Deposited:

2013-09-05

Released:

2013-12-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Brissett, N.C., Martin, M.J., Bartlett, E.J., Bianchi, J., Blanco, L., Doherty, A.J.
Molecular Basis for DNA Double-Strand Break Annealing and Primer Extension by an NHEJ DNA Polymerase. 
Cell Rep, 5, pp. 1108 - 1120, 2013.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 87.58   b = 80.11   c = 118.39 (Ångstroms)

α = 90.0   β = 111.62   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.19969 for 55990 reflections in the resolution range 37.64 to 2.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)