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NDB ID: NA2807    PDB ID: 4O3M     NAKB(beta): NA2807 


Title:

TERNARY COMPLEX OF BLOOM'S SYNDROME HELICASE

Molecular Description:

Bloom syndrome protein (E.C.3.6.4.12)

Deposited:

2013-12-18

Released:

2014-03-12

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Swan, M.K., Legris, V., Tanner, A., Reaper, P.M., Vial, S., Bordas, R., Pollard, J.R., Charlton, P.A., Golec, J.M., Bertrand, J.A.
Structure of human Bloom's syndrome helicase in complex with ADP and duplex DNA. 
Acta Crystallogr.,Sect.D, 70, pp. 1465 - 1475, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 100.93   b = 164.68   c = 50.98 (Ångstroms)

α = 90.0   β = 90.14   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.1829 for 34639 reflections in the resolution range 35.91 to 2.3 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)