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NDB ID: NA2946    PDB ID: 4OAV 


Title:

COMPLETE HUMAN RNASE L IN COMPLEX WITH 2-5A (5'-PPP HEPTAMER), AMPPCP AND RNA SUBSTRATE.

Molecular Description:

RNase L

Deposited:

2014-01-06

Released:

2014-03-12

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Han, Y., Donovan, J., Rath, S., Whitney, G., Chitrakar, A., Korennykh, A.
Structure of human RNase L reveals the basis for regulated RNA decay in the IFN response. 
Science, 343, pp. 1244 - 1248, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 58.61   b = 160.7   c = 230.8 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1995 for 128099 reflections in the resolution range 46.622 to 2.1 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)