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NDB ID: NA2955    PDB ID: 4PU3 


Title:

SHEWANELLA ONEIDENSIS MR-1 TOXIN ANTITOXIN SYSTEM HIPA, HIPB AND ITS OPERATOR DNA COMPLEX (SPACE GROUP P212121)

Molecular Description:

Toxin-antitoxin system toxin HipA family
Toxin-antitoxin system antidote transcriptional repressor Xre family

Deposited:

2014-03-12

Released:

2014-08-06

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Wen, Y., Behiels, E., Felix, J., Elegheert, J., Vergauwen, B., Devreese, B., Savvides, S.N.
The bacterial antitoxin HipB establishes a ternary complex with operator DNA and phosphorylated toxin HipA to regulate bacterial persistence. 
Nucleic Acids Res., 42, pp. 10134 - 10147, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 57.82   b = 122.45   c = 189.85 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.259 for 19187 reflections in the resolution range 49.381 to 3.39 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)