A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 14-Aug-2019 number of released structures: 10334
Search for released structures

NDB ID: NA2993    PDB ID: 4QC7 


Title:

DODECAMER STRUCTURE OF 5-FORMYLCYTOSINE CONTAINING DNA

Molecular Description:

5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(5FC)P*GP*CP*G)-3'

Deposited:

2014-05-09

Released:

2015-02-11

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Szulik, M.W., Pallan, P.S., Nocek, B., Voehler, M., Banerjee, S., Brooks, S., Joachimiak, A., Egli, M., Eichman, B.F., Stone, M.P.
Differential stabilities and sequence-dependent base pair opening dynamics of watson-crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine. 
Biochemistry, 54, pp. 1294 - 1305, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 25.095   b = 41.476   c = 65.692 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.22767 for 5362 reflections in the resolution range 35.07 to 1.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  5.0 sigma(I)