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NDB ID: NA3039    PDB ID: 4QIL 


Title:

CRYSTAL STRUCTURE OF THE ROQ DOMAIN OF HUMAN ROQUIN IN COMPLEX WITH THE HMG19 STEM-LOOP RNA

Molecular Description:

Roquin-1

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Tan, D., Zhou, M., Kiledjian, M., Tong, L.
The ROQ domain of Roquin recognizes mRNA constitutive-decay element and double-stranded RNA. 
Nat.Struct.Mol.Biol., 21, pp. 679 - 685, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 49.6   b = 170.0   c = 51.1 (Ångstroms)

α = 90.0   β = 97.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX (phenix.refine: 1.8.4_1496) program. The R value is 0.1976 for 17984 reflections in the resolution range 37.696 to 2.9 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)