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NDB ID: NA3059    PDB ID: 4QQW     NAKB(beta): NA3059 


Title:

CRYSTAL STRUCTURE OF T. FUSCA CAS3

Molecular Description:

CRISPR-associated helicase
Cas3 family/dna

Deposited:

2014-06-30

Released:

2014-08-27

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Huo, Y., Nam, K.H., Ding, F., Lee, H., Wu, L., Xiao, Y., Farchione, M.D., Zhou, S., Rajashankar, K., Kurinov, I., Zhang, R., Ke, A.
Structures of CRISPR Cas3 offer mechanistic insights into Cascade-activated DNA unwinding and degradation. 
Nat.Struct.Mol.Biol., 21, pp. 771 - 777, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 85.789   b = 218.542   c = 123.749 (Ångstroms)

α = 90.0   β = 105.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.174 for 115323 reflections in the resolution range 30.207 to 2.664 Ångstroms with Fobs >  1.39 sigma(Fobs) and with I >  0.0 sigma(I)