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NDB ID: NA3116    PDB ID: 4QZE 


Title:

MOUSE TDT, F401A MUTANT, IN COMPLEX WITH A DSB SUBSTRATE, C-G BASE PAIR

Molecular Description:

DNA nucleotidylexotransferase (E.C.2.7.7.31)

Deposited:

2014-07-27

Released:

2015-06-10

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Gouge, J., Rosario, S., Romain, F., Poitevin, F., Beguin, P., Delarue, M.
Structural basis for a novel mechanism of DNA bridging and alignment in eukaryotic DSB DNA repair. 
Embo J., 34, pp. 1126 - 1142, 2015.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 58.033   b = 71.608   c = 113.948 (Ångstroms)

α = 90.0   β = 95.19   γ = 90.0 (degrees)

Refinement:

The structure was refined using the BUSTER program. The R value is 0.1938 for 22175 reflections in the resolution range 40.84 to 2.25 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)