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NDB ID: NA3135    PDB ID: 4R2R 


Title:

WILMS TUMOR PROTEIN (WT1) ZINC FINGERS IN COMPLEX WITH CARBOXYLATED DNA

Molecular Description:

Wilms tumor protein
isoform 4/CRA_a

Deposited:

2014-08-12

Released:

2014-10-08

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Olanrewaju, Y.O., Zheng, Y., Wilson, G.G., Zhang, X., Cheng, X.
Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. 
Genes Dev., 28, pp. 2304 - 2313, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 2

Cell Constants:

a = 66.957   b = 77.518   c = 35.585 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1945 for 11418 reflections in the resolution range 29.121 to 2.089 Ångstroms with Fobs >  1.35 sigma(Fobs) and with I >  0.0 sigma(I)