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NDB ID: NA3136    PDB ID: 4R2S 


Title:

WILMS TUMOR PROTEIN (WT1) Q369P ZINC FINGERS IN COMPLEX WITH METHYLATED DNA

Molecular Description:

Wilms tumor protein
isoform 4/CRA_a

Deposited:

2014-08-12

Released:

2014-10-08

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Hashimoto, H., Olanrewaju, Y.O., Zheng, Y., Wilson, G.G., Zhang, X., Cheng, X.
Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. 
Genes Dev., 28, pp. 2304 - 2313, 2014.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 69.148   b = 66.575   c = 36.073 (Ångstroms)

α = 90.0   β = 93.32   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2104 for 5644 reflections in the resolution range 29.361 to 2.489 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)