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NDB ID: NA3383    PDB ID: 5FMZ 


Title:

CRYSTAL STRUCTURE OF INFLUENZA B POLYMERASE WITH BOUND 5' VRNA

Molecular Description:

POLYMERASE ACIDIC PROTEIN
RNA-DIRECTED RNA POLYMERASE CATALYTIC SUBUNIT (E.C.2.7.7.48)
POLYMERASE BASIC PROTEIN 2

Deposited:

2015-11-10

Released:

2016-01-13

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 3 protein sequences

Primary Citation:

Thierry, E., Guilligay, D., Kosinski, J., Bock, T., Gaudon, S., Round, A., Pflug, A., Hengrung, N., El Omari, K., Baudin, F., Hart, D.J., Beck, M., Cusack, S.
Influenza Polymerase Can Adopt an Alternative Configuration Involving a Radical Repacking of Pb2 Domains. 
Mol.Cell, 61, pp. 125 - , 2016.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 126.57   b = 200.54   c = 133.13 (Ångstroms)

α = 90.0   β = 107.7   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.25595 for 83996 reflections in the resolution range 126.83 to 3.4 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)