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NDB ID: PD0005    PDB ID: 2HMI 


Title:

HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX

Molecular Description:

HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX

Deposited:

1998-04-10

Released:

1998-10-14

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASE

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Ding, J., Das, K., Hsiou, Y., Sarafianos, S.G., Clark Jr., A.D., Jacobo-Molina, A., Tantillo, C., Hughes, S.H., Arnold, E.
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution. 
J.Mol.Biol., 284, pp. 1095 - 1111, 1998.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 1 2

Cell Constants:

a = 169.0   b = 169.0   c = 221.0 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.0 for 63413 reflections in the resolution range 8.0 to 2.8 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)