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NDB ID: PD0051    PDB ID: 1CKT 


Title:

CRYSTAL STRUCTURE OF HMG1 DOMAIN A BOUND TO A CISPLATIN-MODIFIED DNA DUPLEX

Molecular Description:

HIGH MOBILITY GROUP PROTEIN HMG1/DNA COMPLEX

Deposited:

1999-04-23

Released:

1999-06-30

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Ohndorf, U.M., Rould, M.A., He, Q., Pabo, C.O., Lippard, S.J.
Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. 
Nature, 399, pp. 708 - 712, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

C 1 2 1

Cell Constants:

a = 105.21   b = 50.41   c = 53.13 (Ångstroms)

α = 90.0   β = 99.82   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.238 for 17638 reflections in the resolution range 100.0 to 2.5 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)