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NDB ID: PD0076    PDB ID: 2IRF 


Title:

CRYSTAL STRUCTURE OF AN IRF-2/DNA COMPLEX.

Molecular Description:

INTERFERON REGULATORY FACTOR 2/DNA COMPLEX

Deposited:

1999-05-30

Released:

1999-10-08

Structural Keywords:

B DOUBLE HELIX, FLIPPED-OUT BASES, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Fujii, Y., Shimizu, T., Kusumoto, M., Kyogoku, Y., Taniguchi, T., Hakoshima, T.
Crystal structure of an IRF-DNA complex reveals novel DNA recognition and cooperative binding to a tandem repeat of core sequences. 
EMBO J., 18, pp. 5028 - 5041, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 65 2 2

Cell Constants:

a = 132.3   b = 132.3   c = 296.5 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.202 for 35660 reflections in the resolution range 10.0 to 2.2 Ångstroms with Fobs >  1.0 sigma(Fobs) and with I >  0.0 sigma(I)