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NDB ID: PD0092    PDB ID: 1CQT 


Title:

CRYSTAL STRUCTURE OF A TERNARY COMPLEX CONTAINING AN OCA-B PEPTIDE, THE OCT-1 POU DOMAIN, AND AN OCTAMER ELEMENT

Molecular Description:

POU DOMAIN
CLASS 2
TRANSCRIPTION FACTOR 1/POU DOMAIN
CLASS 2
ASSOCIATING FACTOR 1/DNA COMPLEX

Deposited:

1999-08-11

Released:

1999-11-15

Structural Keywords:

B DOUBLE HELIX, OVERHANGING BASES

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Chasman, D., Cepek, K., Sharp, P.A., Pabo, C.O.
Crystal structure of an OCA-B peptide bound to an Oct-1 POU domain/octamer DNA complex: specific recognition of a protein-DNA interface. 
Genes Dev., 13, pp. 2650 - 2657, 1999.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 41 21 2

Cell Constants:

a = 93.722   b = 93.722   c = 152.651 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the X-PLOR program. The R value is 0.264 for 11708 reflections in the resolution range 30.0 to 3.2 Ångstroms with Fobs >  2.0 sigma(Fobs) and with I >  0.0 sigma(I)